The SABRE (Southall and Brent REvisited) study started over 30 years ago between 1988 and 1991. The study was set up at University College London (UCL) to study health in mid-life in a group of nearly 5000 people of European, South Asian and African or African Caribbean origins. Study participants were selected at random from the GP practices and workplaces in the London boroughs of Brent and Southall.
The focus of the study is on health in ageing, including health of the heart and cardiovascular system, physical and brain function, metabolic health (for example diabetes). The study examines how mid-life health, lifestyle and social factors affect health in older age and aims to improve understanding of the reasons underlying ethnic group differences in health.
Participants, now in their 70s, 80s and 90s, have been studied 3 times since they were first selected. In the most recent wave of follow-up (2014-2019), participants’ partners were also invited to join along with some new participants of African or African Caribbean origin. Participants completed questionnaires and attended clinics at Ealing Hospital and Wembley Stadium back in 1988-1991 and since then have completed more questionnaires about their health and lifestyles and many have attended our clinics at St Mary’s Hospital and most recently at University College London where they underwent some very detailed health tests including MRI scans of the brain and tests of cognitive function.
The study is funded by two registered charities- British Heart Foundation and the Wellcome Trust. The study team is led by Professor Nish Chaturvedi and based at the MRC Unit for Lifelong Health and Ageing at UCL.
For more information on the findings for the different waves: