SABRE Visit 3 (25 year follow-up visit) started in July 2014 and will end in January 2018. We are grateful to the British Heart Foundation for funding this research programme.
We are inviting SABRE participants, their partners and new African Caribbean participants to come to our clinic at University College London. We will also ask them to complete 3 questionnaires about their health and lifestyle and to give permission for us to link to some of their health-related records, for example, regarding hospital admissions and GP visits.
The aims of the study are to build on what we have learned already from the first study and from visit 2(2008-2011). We will measure changes in the health of the heart and circulation, with a special focus on the health of the blood vessels of the brain, as well as early signs of diabetes. We also want to look at physical function and how well (or otherwise) people are keeping as they get older.
The more we understand about what causes these problems, the more likely we are to be able to work out how to prevent or to treat them in people of all ethnicities.
In our clinic we carry out detailed measurements of blood pressure and assess the health of the heart and large and small blood vessel using non-invasive measurements, such as echocardiography. We will carry out MRI scans of the brain, together with a test of memory and problem solving as at visit 2. We will measure levels of glucose and fats in the blood as well as some markers of inflammation and how well the liver, kidneys and lungs are working. There will be some simple tests of balance and eyesight. A short exercise test (walking) will measure how well the heart and circulation are working during exercise.
Participants and their partners who are unable to visit our clinic can still take part in the study by completing the health and lifestyle questionnaires and /or by giving permission for us to link to their health-related records so that we can follow-up their health.
Click here to access Participant information sheets for the study.